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Intracranial Pharmacotherapy and Pain Assays in Rodents
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Neuroscience
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JoVE Journal Neuroscience
Intracranial Pharmacotherapy and Pain Assays in Rodents

Intracranial Pharmacotherapy and Pain Assays in Rodents

DOI:
10.3791/58473-v

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02:26 min

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April 09, 2019

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, ,
1Department of Anesthesiology, Perioperative Care and Pain Medicine,New York University School of Medicine, 2Department of Neuroscience and Physiology,New York University School of Medicine

Chapters

  • 00:04Title
  • 00:20Study Drug Injection and Analgesia Response Analysis
  • 01:30Results: Intracranial AMPAkine Injection and Systemic Morphine Injection Provide Complementary Analgesia
  • 01:55Conclusion

Summary

Automatic Translation

Automatic Translation

Here we present a protocol to perform intracranial pharmacological experiments followed by pain behavior assays in rodents. This protocol allows researchers to deliver molecular and cellular targets in the brain, for pharmacologic agents in the treatment of pain.

Tags

Intracranial PharmacotherapyPain AssaysRodentsHargreaves ApparatusIntracranial InjectionsAMPAkineMorphineCentral Mechanisms Of PainBrain RegionPain Modulation

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