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Bioengineering

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JoVE Journal Bioengineering
Tredimensionella vävnadstekniska justerad Astrocyten nätverk att Recapitulate utvecklingsmässiga mekanismer och underlätta nervsystemet regenerering
Synthesis, Assembly, and Characterization of Monolayer Protected Gold Nanoparticle Films for Protein Monolayer Electrochemistry
Journal (Bioengineering)
Synthesis, Assembly, and Characterization of Monolayer Protected Gold Nanoparticle Films for Protein Monolayer Electrochemistry
Patterning the Geometry of Human Embryonic Stem Cell Colonies on Compliant Substrates to Control Tissue-Level Mechanics
Journal (Bioengineering)
Patterning the Geometry of Human Embryonic Stem Cell Colonies on Compliant Substrates to Control Tissue-Level Mechanics
 
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Tredimensionella vävnadstekniska justerad Astrocyten nätverk att Recapitulate utvecklingsmässiga mekanismer och underlätta nervsystemet regenerering

Article DOI: 10.3791/55848-v • 08:56 min • January 10th, 2018
January 10th, 2018 •
*1,2,3, *1,2,4, 1,2,4, 1,2, 1,5, 1,5, 1,2,4, 1,2,5
1Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, 2Center for Neurotrauma, Neurodegeneration & Restoration, Michael J. Crescenz Veterans Affairs Medical Center, 3School of Biomedical Engineering, Drexel University, 4Department of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, 5Neuroscience Graduate Group, Perelman School of Medicine, University of Pennsylvania
* These authors contributed equally

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Vi visa upp utvecklingen av själv monterade, tredimensionell buntar av längdriktningen justerad astrocytic somata och processer inom en roman biomaterial fodral. Dessa konstruerade ”levande ställningar”, uppvisar micron-skala diameter ännu att utvidga centimeter i längd, kan fungera som test-sängar att studera nervsystemets mekanismer eller underlätta neuroregeneration av rikta neuronala migration och/eller axonal pathfinding.

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Bioteknik fråga 131 nervvävnad ingenjörsvetenskap levande ställningar neurotrauma neuroregeneration cellmigration axon pathfinding astrocyt nätverk neurala stamceller
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