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Journal / Cancer Research / 通过将表达的腺病毒注射到小鼠乳腺腺中,模拟乳腺癌…
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JoVE Journal Cancer Research
通过将表达的腺病毒注射到小鼠乳腺腺中,模拟乳腺癌
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通过将表达的腺病毒注射到小鼠乳腺腺中,模拟乳腺癌

Article DOI: 10.3791/59502-v • 06:29 min • June 7th, 2019
June 7th, 2019 •
1,2, 1,2, 1,2
1Division of Genetics, Department of Medicine, Brigham and Women's Hospital, 2Department of Medicine, Harvard Medical School

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该协议的目的是描述一种新的乳腺癌建模方法,该方法基于将Cre-表达腺病毒注射到小鼠乳腺的电位内。这种方法允许以时间控制的方式对致癌事件进行细胞型和器官特异性操作。

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癌症研究 问题 148 乳腺癌 乳腺肿瘤 小鼠建模 内电间注射 乳腺 细胞起源 乳腺上皮细胞 Cre/loxP重组 腺病毒
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