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Anesthesie en intubatie van preadolescente muispups voor cardiothoracale chirurgie
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Anesthesie en intubatie van preadolescente muispups voor cardiothoracale chirurgie

Article DOI: 10.3791/64004-v • 09:47 min • June 2nd, 2022
June 2nd, 2022 •
*1, 1,2, 3,4, 1,2, 1,2, *1,2
1Molecular Cardiology and Biophysics Division, Victor Chang Cardiac Research Institute, 2St Vincent’s Clinical School, University of New South Wales Sydney, 3Department of Anaesthesia, The Children’s Hospital at Westmead, 4School of Child and Adolescent Health, University of Sydney
* These authors contributed equally

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Cardiothoracale chirurgische modellen bij muizen >7 dagen oud vereisen intubatie, maar dit is een uitdaging voor preadolescente (8-14 dagen oude) muispups en er is weinig informatie over anesthetische regimes voor intubatie. Hier presenteren we doseringsschema's van ketamine / xylazine / atropine in 10 dagen oude C57BL / 6J-muispups die endotracheale intubatie mogelijk maken, terwijl de diersterfte wordt geminimaliseerd.

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Biologie Nummer 184
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