Intravital photoswitching and tracking of Dendra2-labeled tumor cells through the Mammary Imaging Window is a technique which allows us to image the metastatic behavior of tumor cells in chosen tumor microenvironments over a timescale of days.
Gligorijevic, B., Kedrin, D., Segall, J. E., Condeelis, J., van Rheenen, J. Dendra2 Photoswitching through the Mammary Imaging Window. J. Vis. Exp. (28), e1278, doi:10.3791/1278 (2009).