/

/

建立颅内脑肿瘤异种移植肿瘤的生长和对治疗的反应与后续利用生物发光成像分析

JoVE Journal
Neuroscience

This content is Free Access.

JoVE Journal Neuroscience

Establishing Intracranial Brain Tumor Xenografts With Subsequent Analysis of Tumor Growth and Response to Therapy using Bioluminescence Imaging

Please note that all translations are automatically generated. Click here for the English version.

建立颅内脑肿瘤异种移植肿瘤的生长和对治疗的反应与后续利用生物发光成像分析

DOI:

•

11:09 min

•

July 13, 2010

•

Tomoko Ozawa, C. David James

¹Department of Neurological Surgery,University of California, San Francisco – UCSF

Chapters

00:00Title
00:57Introduction
01:19Tumor Cell Preparation
02:44Tumor Cell Implantation
06:51Bioluminsecence Monitoring of Tumor Growth
07:49Image Analysis
08:59Brain Excision and Fixation
09:22Representative Results
10:39Conclusion

Summary

Automatic Translation

可以建立荧光素酶修饰人脑肿瘤异种移植，颅内无胸腺小鼠，随后的监测肿瘤的生长和治疗用生物发光成像。在与生存分析相结合，生物发光监测是一个重要的研究工具疗法被认为是治疗脑肿瘤的临床前测试。

Tags

Intracranial Brain Tumor Xenografts Tumor Growth Therapy Response Bioluminescence Imaging Transplantation Models Neuro-oncology Research Human Tumor Xenograft Subcutaneous Injection Immunocompromised Mice Orthotopic Xenograft Establishment Neuroanatomical Structures Intracranial Xenograft Establishment Tumor Burden Non-invasive Imaging Bioluminescence Monitoring Orthotopic Brain Tumor Establishment Experimental Therapies

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

脑成像的情感对认知损害的影响调查

启用高灰度分辨率的显示器和传统计算机准确的响应时间测量

人类胶质母细胞瘤肿瘤细胞的分离和扩大使用的神经球含量

使用功能磁共振成像和弥散加权成像脑结构与功能分析

谱系重编程的成人大脑的周细胞源性细胞诱导成神经细胞

用优化的n-甲基 d-葡乙胺保护恢复法制备急性脑切片

在脑核糖凝视与原子力显微镜

用3D 运动捕捉对无上肢损伤患者饮酒任务的运动学分析

利用 SPM 软件分析颅内脑电图数据的神经活动和连接性

轻度创伤性脑损伤大鼠海马学的高级扩散成像

Read Article