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建立颅内脑肿瘤异种移植肿瘤的生长和对治疗的反应与后续利用生物发光成像分析
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Neuroscience
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JoVE Journal
Neuroscience
Establishing Intracranial Brain Tumor Xenografts With Subsequent Analysis of Tumor Growth and Response to Therapy using Bioluminescence Imaging
Please note that all translations are automatically generated.
Click here for the English version.
建立颅内脑肿瘤异种移植肿瘤的生长和对治疗的反应与后续利用生物发光成像分析
DOI:
10.3791/1986-v
•
11:09 min
•
July 13, 2010
•
Tomoko Ozawa
,
C. David James
1
Department of Neurological Surgery
,
University of California, San Francisco – UCSF
Chapters
00:00
Title
00:57
Introduction
01:19
Tumor Cell Preparation
02:44
Tumor Cell Implantation
06:51
Bioluminsecence Monitoring of Tumor Growth
07:49
Image Analysis
08:59
Brain Excision and Fixation
09:22
Representative Results
10:39
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
可以建立荧光素酶修饰人脑肿瘤异种移植,颅内无胸腺小鼠,随后的监测肿瘤的生长和治疗用生物发光成像。在与生存分析相结合,生物发光监测是一个重要的研究工具疗法被认为是治疗脑肿瘤的临床前测试。
Tags
Intracranial Brain Tumor Xenografts
Tumor Growth
Therapy Response
Bioluminescence Imaging
Transplantation Models
Neuro-oncology Research
Human Tumor Xenograft
Subcutaneous Injection
Immunocompromised Mice
Orthotopic Xenograft Establishment
Neuroanatomical Structures
Intracranial Xenograft Establishment
Tumor Burden
Non-invasive Imaging
Bioluminescence Monitoring
Orthotopic Brain Tumor Establishment
Experimental Therapies
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