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Neuroscience
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定向脑深部结构与配送药品,病毒载体,或细胞移植Microinjections
JoVE Journal
Neuroscience
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JoVE Journal
Neuroscience
Targeting of Deep Brain Structures with Microinjections for Delivery of Drugs, Viral Vectors, or Cell Transplants
Please note that all translations are automatically generated.
Click here for the English version.
定向脑深部结构与配送药品,病毒载体,或细胞移植Microinjections
DOI:
10.3791/2082-v
•
07:00 min
•
December 01, 2010
•
Oscar Gonzalez-Perez
,
Hugo Guerrero-Cazares
,
Alfredo Quiñones-Hinojosa
1
Neuroscience Lab/ Fac. Psicologia
,
University of Colima
,
2
Department of Neurosurgery
,
Johns Hopkins University
Chapters
00:05
Title
00:55
Introduction
01:18
Constructing Glass Needles
02:36
Using the Needles for Microinjections into the Rodent Brain
06:06
Representative Microinjection Results
06:36
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
在这篇文章中,我们将展示一种方法,使与50微米的管腔玻璃毛细管针。这种技术大大降低大脑的损害,最大限度地减少药物的被动扩散,并允许一个精确的定位到啮齿类动物的大脑。
Tags
Deep Brain Structures
Microinjections
Drug Delivery
Viral Vectors
Cell Transplants
Brain Parenchyma
Injecting Needle
Brain Lesion
Mouse Brain
Glass Capillary Needles
Brain Damage
Precise Targeting
Rodent Brain
Small Volumes
Bleeding Risks
Passive Diffusion
Injection Techniques
Collateral Damage
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