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定向脑深部结构与配送药品，病毒载体，或细胞移植Microinjections
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JoVE Journal Neuroscience
Targeting of Deep Brain Structures with Microinjections for Delivery of Drugs, Viral Vectors, or Cell Transplants
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定向脑深部结构与配送药品，病毒载体，或细胞移植Microinjections

DOI:
10.3791/2082-v

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07:00 min

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December 01, 2010

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, ,
1 Neuroscience Lab/ Fac. Psicologia,University of Colima, 2Department of Neurosurgery,Johns Hopkins University

Chapters

  • 00:05Title
  • 00:55Introduction
  • 01:18Constructing Glass Needles
  • 02:36Using the Needles for Microinjections into the Rodent Brain
  • 06:06Representative Microinjection Results
  • 06:36Conclusion

Summary

Automatic Translation

Automatic Translation

在这篇文章中，我们将展示一种方法，使与50微米的管腔玻璃毛细管针。这种技术大大降低大脑的损害，最大限度地减少药物的被动扩散，并允许一个精确的定位到啮齿类动物的大脑。

Tags

Deep Brain StructuresMicroinjectionsDrug DeliveryViral VectorsCell TransplantsBrain ParenchymaInjecting NeedleBrain LesionMouse BrainGlass Capillary NeedlesBrain DamagePrecise TargetingRodent BrainSmall VolumesBleeding RisksPassive DiffusionInjection TechniquesCollateral Damage

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