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1Division of Cardiovascular Medicine, Department of Medicine,Vanderbilt University School of Medicine, 2Department of Pharmacology,Vanderbilt University School of Medicine, 3Vanderbilt Institute of Chemical Biology,Vanderbilt University School of Medicine, 4Research Medicine, Veterans Affairs TVHS,Vanderbilt University School of Medicine
Chapters
- 00:05Title
- 00:40Introduction
- 01:02Zebrafish Egg Collection and 96-Well Plate Preparatin
- 02:52Small Molecule Library
- 04:23Screening for Effects of Small Molecules by Visual Inspection of Phenotypes
- 05:51Small Molecule Detection with Zebrafish Chemical Screening Assay
- 06:21Conclusion
Pez cebra se ha convertido en un poderoso<em> In vivo</em> Plataforma para las pantallas de drogas basada en el fenotipo y el análisis químico genético. Aquí, demostramos un método sencillo y práctico a gran escala de detección de moléculas pequeñas con embriones de pez cebra.
