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Chapters
- 00:03Introduction
- 01:17Current Strategies for Controlling Dengue/Malaria Transmission
- 02:30Population Replacement Strategy
- 04:29Effector Genes and Mosquito Physiology
- 06:18Gene Drive Systems
- 07:54Design Criteria for Gene Drive Systems
- 10:50Conditions that Must be Met before Implementing Population Replacem
- 12:28Ethical Consideratons Regarding the Release of Genetically-Modified
- 13:311. Host Country`s Regulatory Infrastructure
- 13:312. Community Consent
- 16:573. Participation of Individuals at Field Sites
- 17:35End Credits
In this candid interview, Anthony A. James explains how mosquito genetics can be exploited to control malaria and dengue transmission. Population replacement strategy, the idea that transgenic mosquitoes can be released into the wild to control disease transmission, is introduced as well as the concept of genetic drive and the design criterion for an effective genetic drive system. The ethical considerations of releasing genetically-modified organisms into the wild are also discussed.
