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准备在鼠害外伤性癫痫的底切模型
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Neuroscience
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JoVE Journal Neuroscience
Preparing Undercut Model of Posttraumatic Epileptogenesis in Rodents
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准备在鼠害外伤性癫痫的底切模型

DOI:
10.3791/2840-v

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07:58 min

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September 15, 2011

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, , ,
1Department of Anatomy and Cell Biology, Department of Neurosurgery, Stark Neuroscience Research Institute,Indiana University School of Medicine

Chapters

  • 00:05Title
  • 01:28Making a Simple Device for Undercut Surgery
  • 03:02Preparation of the Animal for Surgery
  • 04:31Performing the Undercut Procedure
  • 06:57Results of the Undercut Procedure
  • 07:24Conclusion

Summary

Automatic Translation

Automatic Translation

部分隔离皮层（“削弱”）是外伤性癫痫的有效的动物模型。在这里，我们将演示如何使一个新的手术设备，并用它来进行更精确和一致的病变，产生这种模式。

Tags

Undercut ModelPosttraumatic EpileptogenesisRodentsSurgical ProcedureSensorimotor CortexWhite MatterIsolated CortexCerebral CortexBrain SlicesEpileptiform DischargesElectrical SeizuresBehavior SeizuresAnimal ModelTraumatic Brain InjuryPrecise Cortical LesionsSmall Rodent BrainSurgery TechniqueSurgical DeviceCutting DepthCutting AngleConsistent ResultsStudy On Mechanisms

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