We present a microfluidic approach for the expression of protein arrays. The device consists of thousands of reaction chambers controlled by micro-mechanical valves. The microfluidic device is mated to a microarray-printed gene library. These genes are then transcribed and translated on-chip, resulting in a protein array ready for experimental use.
Glick, Y., Avrahami, D., Michaely, E., Gerber, D. High-throughput Protein Expression Generator Using a Microfluidic Platform. J. Vis. Exp. (66), e3849, doi:10.3791/3849 (2012).