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Chapters
- 00:05Title
- 01:28Generating Substrate: Polydimethylsiloxane (PDMS) Slides
- 02:49Generating Substrate: Polyacrylamide (PA) Slide
- 05:57Culturing Mammalian Cells on MEArrays for Functional Analysis
- 09:05Using MEArrays to Analyze How Type I Collagen and P-cadherin Affects Keratin Expression in Multipotent Mammary Epithelial Progenitor Cells
- 11:05Conclusion
Un método combinatorio cribado funcional para obtener ideas sobre los impactos de la composición molecular de los microambientes sobre las funciones celulares se describe. El método aprovecha existentes basados en las tecnologías de microarrays para generar matrices de microambientes definidos combinatorias que soportan la adhesión de células y análisis funcional.
Tags
FabricationUseMicroEnvironment MicroArraysMEArraysInteractionsCellsMicroenvironmentFunctional ConsequencesSingle Cell LevelDifferentiationMigrationProliferation PhenotypesMorphogenesisTumorigenesisCell-cell InteractionsECM InteractionsSoluble Factor InteractionsPhysical CharacteristicsGenomic ContentCombinatorial InteractionsMicroenvironmental ComponentsDistinctive BehaviorsMEArray PlatformCell-based Functional ScreeningMolecular CompositionElastic ModulusMicroarray TechnologyMicropatterning Technology
