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Journal
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Bioengineering
/
片上内皮炎症表型
JoVE Journal
Bioengineering
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JoVE Journal
Bioengineering
On-Chip Endothelial Inflammatory Phenotyping
Please note that all translations are automatically generated.
Click here for the English version.
片上内皮炎症表型
DOI:
10.3791/4169-v
•
12:43 min
•
July 21, 2012
•
J. Sherrod DeVerse*
1
,
Keith A. Bailey*
1
,
Greg A. Foster
,
Vaishali Mittal
,
Stuart M. Altman
,
Scott I. Simon
,
Anthony G. Passerini
1
Department of Biomedical Engineering
,
University of California, Davis
Chapters
00:05
Title
03:04
Substrate Preparation and Cell Culture
04:30
Fabrication of PDMS VMMC
06:37
Cell Shearing
08:30
Monocyte Adhesion Assay
10:55
Representative Results
11:27
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
应用光刻和蚀刻的PDMS制作的微流室探测与欧共体功能障碍和炎症相关的功能性结果。在有代表性的实验,能力差剪应力调节单核细胞粘附因子激活欧共体单层证明。
Tags
On-Chip Endothelial Inflammatory Phenotyping
Atherogenesis
Metabolic Abnormalities
Systemic Inflammation
Endothelial Dysfunction
Functional Changes In Endothelium
Risk Assessment
Therapeutic Strategy
Regulation Of Inflammation
Local Hemodynamics
Non-random Spatial Distribution Of Atherosclerosis
Lab-on-a-chip
Quantitatively Assay Metabolic Perturbation
Inflammatory Events In Endothelial Cells
Monocytes
Flow Conditions
Soft Lithography
Microfabricate Vascular Mimetic Microfluidic Chambers (VMMC)
Cultured EC Monolayers
Imaging Inflammatory Events
Shear Field
Cytokine-induced Inflammation
Lipid-induced Inflammation
RAGE-induced Inflammation
Human Aortic EC (HAEC)
Monocytic Cell Rolling And Arrest
TNF-alpha
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