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Osmotisk Drug Delivery til Iskæmisk bagbensknogler og perfusion af kar med Microfil for Micro-computertomografi Imaging
JoVE Journal
Medicine
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JoVE Journal Medicine
Osmotic Drug Delivery to Ischemic Hindlimbs and Perfusion of Vasculature with Microfil for Micro-Computed Tomography Imaging
DOI:

10:50 min

June 29, 2013

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Chapters

  • 00:05Title
  • 02:47Priming the Osmotic Pump
  • 03:58Creating Unilateral Hindlimb Ischemia in the Mouse
  • 06:30Imaging Specimen Preparation
  • 09:40Results: Representative Perfusion of the Vasculature in the Murine Hindlimb Ischemia Model
  • 10:27Conclusion

Summary

Automatic Translation

Vi viser her<em> In vivo</em> Indsættelse af en osmotisk pumpe til konstant lokale stof levering og etablering af bagbenet iskæmi i en musemodel. Desuden er bagbenet kar perfunderet med Microfil, en silicone stråleuigennemtrængelig agent, for at forberede mikro-computertomografi (mikro-CT).

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