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Etter i Real Time Impact of Pneumokokk virulens faktorer i en akutt Mouse Lungebetennelse Modell Bruke Bioluminescent Bakterier
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
DOI:

11:32 min

February 23, 2014

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Chapters

  • 00:05Title
  • 02:23Preparation of the Infectious Stock of Bioluminescent Pneumococci
  • 03:58Intranasal and Intraperitoneal Infection of Mice
  • 05:38Imaging Pneumococcal Dissemination into the Lung and Blood
  • 07:30Results: Pneumococcal Dissemination in Mice after Intranasal Infection
  • 10:14Conclusion

Summary

Automatic Translation

Streptococcus pneumoniae er den ledende patogen forårsaker alvorlig smittsom lungebetennelse og ansvarlig for over 2 millioner dødsfall på verdensbasis. Virkningen av bakterielle faktorer involvert i fitness eller virulens kan overvåkes i sanntid i en akutt mus lungebetennelse eller bakteriemi modell med selvlysende bakterier.

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