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用奔放的整体体积描记测量呼吸功能的影响
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Biology
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JoVE Journal
Biology
Measuring Respiratory Function in Mice Using Unrestrained Whole-body Plethysmography
Please note that all translations are automatically generated.
Click here for the English version.
用奔放的整体体积描记测量呼吸功能的影响
DOI:
10.3791/51755-v
•
08:51 min
•
August 12, 2014
•
Rebecca Lim
2
,
Marcus J. Zavou
,
Phillipa-Louise Milton
,
Siow Teng Chan
,
Jean L. Tan
,
Hayley Dickinson
2
,
Sean V. Murphy
,
Graham Jenkin
2
,
Euan M. Wallace
2
1
The Ritchie Centre
,
Monash Institute of Medical Research
,
2
Department of Obstetrics and Gynaecology
,
Monash Medical Centre
,
3
Animal Resource Centre, Perth, Australia
,
4
Wake Forest Institute for Regenerative Medicine
Chapters
00:05
Title
01:20
Initial Setup
02:04
Bridge Amplifier Calibration
03:53
Recording Lung Function
05:03
Plethysmography Analysis
07:14
Results: Unrestrained Whole-body Plethysmography (UWBP)
08:07
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
呼吸生理的评估方法时,需要克制的动物或镇静历来依赖。无节制的全身体积描记法,然而,提供了在动物模型中的呼吸生理学的精确,非侵入性,定量分析。此外,该技术允许重复小鼠允许纵向研究的呼吸系统评估。
Tags
Respiratory Function
Unrestrained Whole-body Plethysmography
Lung Function
Respiratory Parameters
Tidal Volume
Minute Volume
Inspiratory Duty Cycle
Inspiratory Flow Rate
Inspiration Time To Expiration Time Ratio
Non-invasive
Quantitative Analysis
Rodent Models
Respiratory Dysfunction
Morbidity
Mortality
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