Utveckling av ett<em> In vitro</em> Modellsystem för att studera interaktionen mellan<em> Equus</em><em> Caballus</em> IgE med sin högaffinitetsreceptor FcsRI
JoVE Journal
Immunology and Infection Author Produced
The current study describes the development and applications of a genetically engineered assay system based on the transfection of rat basophilic leukemia cells with the equine FcεRIα gene. Transfected cells express a functional receptor where the release of mediators of the allergic response can be activated by IgE and antigen.