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Studying Microbial Communities In Vivo: A Model of Host-mediated Interaction Between Candida Albicans and Pseudomonas Aeruginosa in the Airways
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Chapters
- 00:05Title
- 00:39C. albicans Airway Colonization
- 01:47P. aeruginosa-induced Acute Lung Infection
- 04:42Results: Acute Lung Injury Induced by P. aeruginosa
- 05:56Conclusion
While in vitro study of host-pathogen interactions allow the characterization of specific immune responses, in vivo models are required to observe the effects of complex responses. Using Candida albicans exposure followed by Pseudomonas aeruginosa-mediated lung infection, we established a murine model of microbial interactions involved in ventilator-associated pneumonia pathogenicity.
