Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis <em>via</em> Orthotopic Inoculation with Ovarian Carcinoma Cells

Yoshihiro Koya; Hiroaki Kajiyama; Wenting Liu; Kiyosumi Shibata; Takeshi Senga; Fumitaka Kikkawa

doi:10.3791/54353

Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Or...

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JoVE Journal Cancer Research

Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells

Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells

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08:17 min

December 9, 2016

DOI: 10.3791/54353-v

Yoshihiro Koya^1,2, Hiroaki Kajiyama², Wenting Liu^1,2, Kiyosumi Shibata², Takeshi Senga³, Fumitaka Kikkawa²

¹Bell Research Center for Reproductive Health and Cancer, ²Department of Obstetrics and Gynecology,Nagoya University Graduate School of Medicine, ³Department of Cancer Biology,Nagoya University Graduate School of Medicine

To clarify the multistep process of peritoneal dissemination of ovarian carcinoma, the current study presents a murine experimental model of original tumor development and peritoneal metastasis via orthotopic inoculation with these tumor cells.

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Murine Model Ovarian Carcinoma Orthotopic Inoculation Peritoneal Metastasis Tumor Biology Cell Line Preparation Retroperitoneal Approach Nude Mice Epithelial Ovarian Carcinoma Peritoneal Dissemination