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用于评估一般运动、肌肉力量和小鼠协调性的行为测试电池

JoVE Journal
Behavior

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JoVE Journal Behavior

Battery of Behavioral Tests Assessing General Locomotion, Muscular Strength, and Coordination in Mice

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用于评估一般运动、肌肉力量和小鼠协调性的行为测试电池

DOI:

10.3791/55491-v

•

06:54 min

•

January 23, 2018

•

Karlaina JL Osmon, Meera Vyas, Evan Woodley, Patrick Thompson, Jagdeep S Walia^2,3

¹Centre for Neuroscience Studies,Queen’s University, ²Department of Biomedical and Molecular Sciences,Queen’s University, ³Medical Genetics/ Department of Pediatrics, Kingston General Hospital, Centre for Neuroscience Studies, and Department of Biomedical and Molecular Sciences,Queen’s University

Chapters

00:05Title
00:49Open Field Test
02:54Mesh & Rotarod Test
04:45Results: Treated Animals Outperform Untreated Animals
05:31Conclusion

Summary

Automatic Translation

行为测试用于临床试验, 以评估疾病或治疗对动物福祉的表型影响。为了在全球范围内评估电机的功能, 我们选择了一般运动, 肌肉力量和协调的测试: 开放现场测试, 网格测试, 和 rotarod 测试, 分别。

Tags

Behavioral Testing Locomotion Muscular Strength Coordination Mice Open Field Test Mesh Test Rotarod Test Preclinical Trials Movement Motility SmartWare Software Digital Analog Converter Calibration Data Analysis Accelerated Protocol

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