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In vitro Imaging og Kvantificering af Drug Targeting Effektivitet af fluorescens-mærkede GnRH-analoger
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In vitro Imaging og Kvantificering af Drug Targeting Effektivitet af fluorescens-mærkede GnRH-analoger

Article DOI: 10.3791/55529-v • 10:36 min • March 21st, 2017
March 21st, 2017 •
1,2, 1, 1, 1, 3, 2
1MTA-SE Pathobiochemistry Research Group, Semmelweis University, 2Department of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, 3MTA-ELTE Research Group of Peptide Chemistry, Eötvös Loránd University

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Selektivt mærket fluorescerende GnRH-I, -II og-III derivater er pålidelige værktøjer til sporing og kvantificering deres cellulære optagelse. Dette håndskrift introducerer eksperimenter for at visualisere, kvantificere og sammenligne optagelsen effektiviteten af ​​disse GnRH konjugater i forskellige cellelinier.

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Cancer Research målrettet terapi cancer tumor celle konjugat konfokal mikroskopi GnRH FITC FACS CLSM
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