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Automated Gait Analysis in Mice with Chronic Constriction Injury
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JoVE Journal Neuroscience
Automated Gait Analysis in Mice with Chronic Constriction Injury

Automated Gait Analysis in Mice with Chronic Constriction Injury

DOI:
10.3791/56402-v

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06:49 min

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October 17, 2017

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, , , , , ,
1Department of Physiology and Medical Science, College of Medicine and Brain Research Institute,Chungnam National University, 2KM Fundamental Research Division,Korea Institute of Oriental Medicine (KIOM), 3Department of Neuroscience and Cell Biology,University of Texas Medical Branch at Galveston

Chapters

  • 00:05Title
  • 00:42Chronic Constriction Injury (CCI) of the Sciatic Nerve
  • 01:52Assessments: von Frey Test and Automated Gait Analysis
  • 05:01Results: Testing Post-CCI Surgery
  • 06:19Conclusion

Summary

Automatic Translation

Automatic Translation

The precise assessment of pain response in a neuropathic animal model is critical to investigate the pathophysiology of pain diseases and develop new analgesics. We present a sensitive and objective method to determine the sensory function of the rodent hind paw by an automated gait analysis system.

Tags

Keywords: Automated Gait AnalysisChronic Constriction InjuryMechanical AllodyniaVon Frey TestPeripheral Nerve InjuryICR MiceGait ParametersBehavioral TestPlantar SurfacePaw Withdrawal

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