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Síntesis y evaluación de un inhibidor de la absorción de calcio mitocondrial basado en rutenio
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Síntesis y evaluación de un inhibidor de la absorción de calcio mitocondrial basado en rutenio

Article DOI: 10.3791/56527-v • 07:12 min • October 26th, 2017
October 26th, 2017 •
1, 1
1Department of Chemistry and Chemical Biology, Cornell University

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Se presenta un protocolo para la síntesis, purificación y caracterización de un inhibidor basado en rutenio de la absorción de calcio mitocondrial. Un procedimiento para evaluar su eficacia en células de mamífero permeabilized está demostrado.

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Química número 128 Ru360 mitocondrias calcio calcio mitocondrial Uniporter rojo de rutenio química de Bioinorganic
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