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JoVE Journal Developmental Biology
Bruker Human indusert Pluripotent Stamcelle-avledet Hepatocyte-lignende celler for medisiner
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Bruker Human indusert Pluripotent Stamcelle-avledet Hepatocyte-lignende celler for medisiner

Article DOI: 10.3791/57194-v • 12:40 min • May 19th, 2018
May 19th, 2018 •
1, 1, 1
1Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina

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Protokollen presenteres her beskriver en plattform for å identifisere små molekyler for behandling av leversykdommer. En detaljert beskrivelse vises detaljering hvordan skille iPSCs i celler med hepatocyte egenskaper i 96-brønnen plater, og bruke cellene til skjermen for små molekyler med potensielle terapeutisk aktivitet.

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Utviklingsbiologi problemet 135 indusert Pluripotent stilk celler cellekultur Hepatocyte differensiering høy gjennomstrømning Screening Hepatocyte-lignende celler hyperkolesterolemi
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