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En lukket-brystet modell å indusere tverrgående aorta Constriction i mus
JoVE Journal
Medicine
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JoVE Journal Medicine
A Closed-chest Model to Induce Transverse Aortic Constriction in Mice
DOI:

08:10 min

April 05, 2018

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Chapters

  • 00:04Title
  • 01:01Induction of Anesthesia and Intubation
  • 02:57Preoperative Doppler Measurement and Thoracotomy
  • 04:03Banding the Transverse Aorta
  • 05:58Results: Induction of Successful Transverse Aortic Constriction in Mice
  • 07:30Conclusion

Summary

Automatic Translation

Her presenterer vi protokollen tverrgående aorta innsnevring (TAC) via en lateral thoracotomy. Denne teknikken er en minimal invasiv, lukket kiste kirurgisk prosedyre å simulere trykk overbelastning og hjertesvikt i mus utnytte TAC laboratorium standardinnstillinger.

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