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Fluorescens molekylære tomografi for In Vivo billeddannelse af glioblastom Xenografts
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Chapters
- 00:05Title
- 00:55Construct-positive Glioblastoma Cell Sorting
- 02:46Near-infrared Fluorescent Protein (iRFP)-tagged Glioblastoma Cell Intracranial Injection
- 04:49Fluorescence Molecular Tomography (FMT) Imaging and Analysis
- 06:22Results: Representative In Vivo FMT Imaging of Glioblastoma Xenografts
- 07:27Conclusion
Orthotopic intrakraniel injektion af tumorceller har været anvendt i kræftforskning for at studere hjernen tumor biology, progression, evolution og terapeutisk respons. Her præsenterer vi fluorescens molekylære tomografi af tumor xenografts, der giver real-time intravital imaging og kvantificering af en tumor masse i prækliniske glioblastom modeller.
Tags
Fluorescence Molecular TomographyFMTGlioblastoma XenograftsIn Vivo ImagingBrain Tumor BiologyCancer ResearchDrug DiscoveryTumor AggressivenessTumor HeterogeneityTreatment ResponsivenessNon-invasiveQuantitativeXenograft ModelsGlioblastoma CellsLentivirusFluorescent ProteinFlow CytometryCell SortingSingle Cell SuspensionPBSIn Vivo Experiments
