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JoVE Journal
Immunology and Infection

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The Lambda Select cII Mutation Detection System
 

The Lambda Select cII Mutation Detection System

Article DOI: 10.3791/57510
April 26th, 2018

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Summary April 26th, 2018

We describe a detailed protocol for the Lambda Select cII mutation assay in cultured cells of transgenic rodents or the corresponding animals treated with a chemical/physical agent of interest. This approach has been widely used for mutagenicity testing of carcinogens in mammalian cells.

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