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JoVE Journal
Immunology and Infection

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吞噬细胞内复制脓肿分枝杆菌毒力标志物的鉴定
 
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吞噬细胞内复制脓肿分枝杆菌毒力标志物的鉴定

Article DOI: 10.3791/57766
September 27th, 2018

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Summary September 27th, 2018

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在这里, 我们提出两个协议来研究吞噬-分枝杆菌脓肿的相互作用: 座子突变文库的筛选和 RNA 中细菌细胞内转录的测定测 序。这两种方法都提供了对基因组优势和 transcriptomic 适应增强细胞内细菌适应性的洞察力。

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