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June 26, 2018
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本协议的目标是提供一个基于细胞的系统,在体内复制α synuclein 聚合体的形成。细胞内阿尔法-synuclein 包裹体的种子在原代神经元的内化和传播的外源管理的原生微粒相关的阿尔法-synuclein 集分离的病阿尔法 synuclein 转基因小鼠。
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Cite this Article
Panattoni, G., Rota, L., Colla, E. Exogenous Administration of Microsomes-associated Alpha-synuclein Aggregates to Primary Neurons As a Powerful Cell Model of Fibrils Formation. J. Vis. Exp. (136), e57884, doi:10.3791/57884 (2018).
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