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Neuroscience

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Generation and On-Demand Initiation of Acute Ictal Activity in Rodent and Human Tissue
 

Generation and On-Demand Initiation of Acute Ictal Activity in Rodent and Human Tissue

Article doi: 10.3791/57952
January 19th, 2019

Summary January 19th, 2019

Acute seizure models are important for studying the mechanisms underlying epileptiform events. Furthermore, the ability to generate epileptiform events on-demand provides a highly efficient method to study the exact sequence of events underlying their initiation. Here, we describe the acute 4-aminopyridine cortical seizure models established in mouse and human tissue.

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