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Synthesis, Characterization, and Application of Superparamagnetic Iron Oxide Nanoprobes for Extrapulmonary Tuberculosis Detection
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Synthesis, Characterization, and Application of Superparamagnetic Iron Oxide Nanoprobes for Extrapulmonary Tuberculosis Detection

Synthesis, Characterization, and Application of Superparamagnetic Iron Oxide Nanoprobes for Extrapulmonary Tuberculosis Detection

DOI:
10.3791/58227-v

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09:54 min

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February 16, 2020

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, , , , , , , ,
1Department of Pulmonary and Critical Care Medicine,Taipei Medical University-Shuang Ho Hospital, 2Department of Research and Department of Dentistry,Taipei Medical University / Shuang-Ho Hospital, 3Department of Pathology,Taipei Medical University, 4Department of Urology, School of Medicine, College of Medicine,Taipei Medical University, 5McLean Imaging Center,McLean Hospital/Harvard Medical School, 6Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine,Taipei Medical University, 7Department of Medicine,Mackay Medical College, 8Department of Biological Science and Technology,National Chiao Tung University, 9Graduate Institute of Clinical Medicine,Taipei Medical University

Chapters

  • 00:04Title
  • 01:42Superparamagnetic Iron Oxide (SPIO) Nanoparticle Synthesis
  • 02:54SPIO-Mycobacterium tuberculosis Surface Antibody (MtbsAb) Synthesis
  • 04:03Particle Morphology Observation and Relaxation Tier Measurement
  • 04:40Cell Magnetic Resonance Imaging (MRI)
  • 05:41BCG Inoculation
  • 06:13In Vivo MRI
  • 07:30Results: Representative Extrapulmonary Tuberculosis Detection
  • 09:04Conclusion

Summary

Automatic Translation

Automatic Translation

To improve serological diagnostic tests for Mycobacterium tuberculosis antigens, we developed superparamagnetic iron oxide nanoprobes to detect extrapulmonary tuberculosis.

Tags

Keywords: Superparamagnetic Iron Oxide NanoprobesExtrapulmonary Tuberculosis DetectionMycobacterium TuberculosisMRI Contrast AgentDextran-coated Iron Oxide Magnetic NanoparticlesSPIO-conjugated Mycobacterium Tuberculosis Surface Antibodies

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