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Journal
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Developmental Biology
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Hyperandrogenic 小鼠模型研究多囊卵巢综合征
JoVE Journal
Developmental Biology
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JoVE Journal
Developmental Biology
A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome
Please note that all translations are automatically generated.
Click here for the English version.
Hyperandrogenic 小鼠模型研究多囊卵巢综合征
DOI:
10.3791/58379-v
•
08:20 min
•
October 02, 2018
•
Ping Xue
,
Zhiqiang Wang
,
Xiaomin Fu
2
,
Junjiang Wang
3
,
Gopika Punchhi
,
Andrew Wolfe
4
,
Sheng Wu
4,5
1
Department of Pediatrics
,
Johns Hopkins University School of Medicine
,
2
Department of Health
,
Beijing Military General Hospital
,
3
Southern Medical University
,
4
Department of Molecular and Cellular Physiology
,
Johns Hopkins University School of Medicine
,
5
Department of Gynecology and Obstetrics
,
Johns Hopkins University School of Medicine
Chapters
00:04
Title
00:47
Dihydrotestosterone (DHT) Pellet Preparation
02:04
DHT Insertion and Replacement
04:56
Reproductive Profile Assessment of Female Offspring from Chronically DHT-inserted Dams
06:27
Results: Representative Mouse PCOS Model Analyses
07:28
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
我们描述了一个瘦的 pcos 样小鼠模型的发展与 dihydrotestosterone 丸研究 pcos 的病理生理学和这些 pcos 样水坝的后代。
Tags
Polycystic Ovary Syndrome
PCOS
Hyperandrogenism
Dihydrotestosterone
DHT
Mouse Model
Silicone Tubing
Pellet Implantation
Surgical Procedure
Androgen Exposure
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