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JoVE Journal
Chemistry

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Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures
 

Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures

Article DOI: 10.3791/58771-v
January 19th, 2019

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Summary January 19th, 2019

Here, a protocol for the protection of DNA origami nanostructures in Mg-depleted and nuclease-rich media using natural cationic polysaccharide chitosan and synthetic linear polyethyleneimine (LPEI) coatings is presented.

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