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Journal
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Immunology and Infection
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脓毒症诱导免疫抑制的切卡结扎和穿刺和鼻内感染双重模型的设计
JoVE Journal
Immunology and Infection
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JoVE Journal
Immunology and Infection
Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
Please note that all translations are automatically generated.
Click here for the English version.
脓毒症诱导免疫抑制的切卡结扎和穿刺和鼻内感染双重模型的设计
DOI:
10.3791/59386-v
•
07:30 min
•
June 15, 2019
•
Zhihan Wang*
1,2
,
Qinqin Pu*
1,2
,
Ping Lin*
2,3
,
Changlong Li
,
Jianxin Jiang
,
Min Wu
1
West China School of Basic Medical Sciences & Forensic Medicine
,
Sichuan University
,
2
Department of Biomedical Sciences, School of Medicine and Health Sciences
,
University of North Dakota
,
3
State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Surgery Research, Daping Hospital
,
Army Medical University
Chapters
00:00
Title
00:12
Cecal Ligation and Puncture (CLP)
03:29
Secondary Intranasal Infection with
Staphylococcus aureus
05:52
Results
06:59
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
该协议描述了在免疫抑制条件下测量继发医院感染的传染性结果的技术,首先通过建立结扎/穿刺小鼠,然后挑战他们与鼻内感染创建一个临床相关的免疫抑制败血症模型。
Tags
Cecal Ligation
Cecal Puncture
Sepsis
Immunosuppression
Mouse Model
Intranasal Infection
Staphylococcus Aureus
Pneumonia
Article
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