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Journal
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Biochemistry
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通过红外纳米光谱和原子力显微镜对单个蛋白质聚合进行特征化
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Biochemistry
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Biochemistry
Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy
Please note that all translations are automatically generated.
Click here for the English version.
通过红外纳米光谱和原子力显微镜对单个蛋白质聚合进行特征化
DOI:
10.3791/60108-v
•
12:58 min
•
September 12, 2019
•
Francesco Simone Ruggeri
,
Tomas Šneideris
2
,
Sean Chia
,
Michele Vendruscolo
,
Tuomas P. J. Knowles
3
1
Centre for Misfolding Diseases, Department of Chemistry
,
University of Cambridge
,
2
Institute of Biotechnology, Life Sciences Center
,
Vilnius University
,
3
Cavendish Laboratory, Department of Physics
,
University of Cambridge
Chapters
00:04
Title
01:09
Atomic Force Microscopy (AFM) Protein Aggregate Morphology Imaging
05:09
Infrared (IR) Nanospectroscopy Protein Aggregate Measurement
11:57
Results: Individual Protein Aggregated Characterization by IR Nanospectroscopy and AFM
13:30
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
我们描述了红外纳米光谱学和高分辨率原子力显微镜的应用,将蛋白质自组装过程可视化为寡聚体和淀粉样纤维蛋白,这与发病和发展密切相关广泛的人类神经退行性疾病。
Tags
Protein Aggregates
Infrared Nanospectroscopy
Atomic Force Microscopy
Single Molecule Methods
Biomolecular Processes
Nano Scale
Heterogeneous Systems
Protein Aggregation
Biomaterials
Drug Delivery
AFM Parameters
AFM Imaging
AFM Cantilever
AFM Laser Beam
AFM Deflected Beam
AFM Oscillation
AFM Resonance
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