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Journal
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Biochemistry
/
赤外線ナノ分光法と原子間力顕微鏡による個々のタンパク質凝集物の特徴付け
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Biochemistry
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JoVE Journal
Biochemistry
Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy
Please note that all translations are automatically generated.
Click here for the English version.
赤外線ナノ分光法と原子間力顕微鏡による個々のタンパク質凝集物の特徴付け
DOI:
10.3791/60108-v
•
12:58 min
•
September 12, 2019
•
Francesco Simone Ruggeri
,
Tomas Šneideris
2
,
Sean Chia
,
Michele Vendruscolo
,
Tuomas P. J. Knowles
3
1
Centre for Misfolding Diseases, Department of Chemistry
,
University of Cambridge
,
2
Institute of Biotechnology, Life Sciences Center
,
Vilnius University
,
3
Cavendish Laboratory, Department of Physics
,
University of Cambridge
Chapters
00:04
Title
01:09
Atomic Force Microscopy (AFM) Protein Aggregate Morphology Imaging
05:09
Infrared (IR) Nanospectroscopy Protein Aggregate Measurement
11:57
Results: Individual Protein Aggregated Characterization by IR Nanospectroscopy and AFM
13:30
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
赤外線ナノ分光法と高分解能原子間近顕微鏡の応用を用いて、タンパク質自己組織化のプロセスをオリゴメラ凝集体とアミロイド線維に可視化し、発症と発達に密接に関連している。ヒト神経変性疾患の広い範囲の。
Tags
Protein Aggregates
Infrared Nanospectroscopy
Atomic Force Microscopy
Single Molecule Methods
Biomolecular Processes
Nano Scale
Heterogeneous Systems
Protein Aggregation
Biomaterials
Drug Delivery
AFM Parameters
AFM Imaging
AFM Cantilever
AFM Laser Beam
AFM Deflected Beam
AFM Oscillation
AFM Resonance
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