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赤外線ナノ分光法と原子間力顕微鏡による個々のタンパク質凝集物の特徴付け
JoVE Journal
Biochemistry
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JoVE Journal Biochemistry
Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy
DOI:

12:58 min

September 12, 2019

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Chapters

  • 00:04Title
  • 01:09Atomic Force Microscopy (AFM) Protein Aggregate Morphology Imaging
  • 05:09Infrared (IR) Nanospectroscopy Protein Aggregate Measurement
  • 11:57Results: Individual Protein Aggregated Characterization by IR Nanospectroscopy and AFM
  • 13:30Conclusion

Summary

Automatic Translation

赤外線ナノ分光法と高分解能原子間近顕微鏡の応用を用いて、タンパク質自己組織化のプロセスをオリゴメラ凝集体とアミロイド線維に可視化し、発症と発達に密接に関連している。ヒト神経変性疾患の広い範囲の。

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