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Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments
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Chapters
- 00:05Introduction
- 00:44Translaminar Autonomous System (TAS) Setup
- 01:42Human Whole Eye Globe Preparation
- 02:24IOP (Bottom) Chamber Setup
- 03:20ICP (Top) Chamber Setup
- 03:52Data Recording System Setup
- 06:56Results: Representative Translaminar Autonomous System Model Analyses
- 08:26Conclusion
We describe and detail the use of the translaminar autonomous system. This system utilizes the human posterior segment to independently regulate the pressure inside the segment (intraocular) and surrounding the optic nerve (intracranial) to generate a translaminar pressure gradient that mimics features of glaucomatous optic neuropathy.
Tags
Translaminar Autonomous SystemIntraocular PressureIntracranial PressurePosterior SegmentEx VivoPreclinicalGlaucomaTraumatic Brain InjuryIdiopathic Intracranial HypertensionSpaceflight-associated Neuro-ocular SyndromePerfusion FluidSyringeFilterTubingOptic NerveVitreous HumorRetinaEpoxy ResinO-ringScrewsIOP Chamber
