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测量在C.elegan的RAN肽毒性
JoVE Journal
Biology
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JoVE Journal Biology
Measuring RAN Peptide Toxicity in C. elegans
DOI:

10:49 min

April 30, 2020

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Chapters

  • 00:04Introduction
  • 01:05Measurement of the Developmental Toxicity of RAN Peptides following RNAi-based Gene Knockdown
  • 05:38Post-developmental RAN Peptide Paralysis Assay
  • 08:02Results: Toxicity of RAN Peptides
  • 10:04Conclusion

Summary

Automatic Translation

重复相关非ATG相关转化产品是几种重复扩张性疾病的病原特征。所述协议的目的是使用模型系统C.elegans的行为和细胞测定来评估这些肽引起的毒性。

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