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测量在C.elegan的RAN肽毒性

JoVE Journal
Biology

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JoVE Journal Biology

Measuring RAN Peptide Toxicity in C. elegans

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测量在C.elegan的RAN肽毒性

6,468 Views

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10:49 min

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April 30, 2020

DOI:

10.3791/61024-v

DOI:

10.3791/61024-v

•

10:49 min

April 30, 2020

•

1 Views

Paige Rudich¹, Carley Snoznik², Noah Puleo², Todd Lamitina^1,2

¹Graduate Program in Cell Biology and Molecular Physiology,University of Pittsburgh, ²Department of Pediatrics,University of Pittsburgh School of Medicine

Summary

重复相关非ATG相关转化产品是几种重复扩张性疾病的病原特征。所述协议的目的是使用模型系统C.elegans的行为和细胞测定来评估这些肽引起的毒性。

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