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Biology

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量化秀丽隐杆线虫中组织特异性蛋白静剂下降
 
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量化秀丽隐杆线虫中组织特异性蛋白静剂下降

Article DOI: 10.3791/61100-v 09:18 min September 7th, 2021
September 7th, 2021

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Summary

Please note that all translations are automatically generated.

Click here for the English version.

蛋白质静力学下降是衰老的标志,促进神经退行性疾病的发作。我们概述了一种方案,通过融合到荧光报告基因的多谷氨酰胺重复序列的异源表达来量化两种不同 秀丽隐杆线虫 组织中的蛋白质稳态。该模型允许对蛋白质稳态进行快速体内遗传分析。

Tags

生物学,第175期,蛋白质平衡,聚谷氨酰胺,polyQ::YPC,秀丽隐杆线虫,衰老,生物标志物,蛋白质稳态,遗传分析,功能基因组学
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