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Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
 

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice

Article DOI: 10.3791/61547-v
June 28th, 2021

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Summary June 28th, 2021

Animal models for severe acute pancreatitis enable the study of pathophysiological changes at the initial stage, facilitating observation of the evolution of inflammatory events. Here we provide a protocol for the induction of severe acute biliary pancreatitis by retrograde infusion of sodium taurocholate into the pancreatic duct of anesthetized C57BL/6 mice.

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