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Near Infrared Photoimmunotherapy for Mouse Models of Pleural Dissemination
Near Infrared Photoimmunotherapy for Mouse Models of Pleural Dissemination
JoVE Journal
Medicine
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JoVE Journal Medicine
Near Infrared Photoimmunotherapy for Mouse Models of Pleural Dissemination

Near Infrared Photoimmunotherapy for Mouse Models of Pleural Dissemination

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05:39 min

February 09, 2021

DOI:

05:39 min
February 09, 2021

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Summary

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Near-infrared photoimmunotherapy (NIR-PIT) is an emerging cancer therapeutic strategy that utilizes an antibody-photoabsorber (IR700Dye) conjugate and NIR light to destroy cancer cells. Here, we present a method to evaluate the antitumor effect of NIR-PIT in a mouse model of pleural disseminated lung cancer and malignant pleural mesothelioma using bioluminescence imaging.

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