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LQ α和β参数、辐射剂量模式和体内剂量沉积评估的辐照器调试和剂量测量
JoVE Journal
Biology
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JoVE Journal Biology
Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
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LQ α和β参数、辐射剂量模式和体内剂量沉积评估的辐照器调试和剂量测量

DOI:
10.3791/61692-v

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06:20 min

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March 11, 2021

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, , , , ,
1Department of Basic Pharmaceutical Sciences, School of Pharmacy,West Virginia University, 2Radiation Oncology,West Virginia University, 3School of Medicine,West Virginia University, 4Department of Neuroscience,West Virginia University

Chapters

  • 00:05Introduction
  • 01:14Dose Output Determination
  • 02:12Radiochromic Film Calibration Curve Creating
  • 03:26Alpha/beta and Specific Dose Output Value Determination
  • 04:22Beam Positioning for Mouse Tumor Treatment
  • 04:52Results: Representative Irradiator Commissioning and Dosimetry
  • 05:28Conclusion

Summary

Automatic Translation

Automatic Translation

辐射剂量为提高临床前实验的准确性和确保所提供的辐射剂量与临床参数密切相关提供了技术。该协议描述了在学前辐射实验期间每个阶段要采取的步骤，以确保适当的实验设计。

Tags

Irradiator CommissioningDosimetryLQ α And β ParametersRadiation Dosing SchemaIn Vivo Dose DepositionRadiobiologyRadiation Therapy ExperimentsDosimetric CalibrationIonization ChamberRadiochromic FilmImageJPreclinical Radiation TherapyTranslational Relevance

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