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Injicerbara supramolecular Polymer-Nanopartikelhydrogeler för cell- och läkemedelsleveransapplikationer
JoVE Journal
Bioengineering
This content is Free Access.
JoVE Journal Bioengineering
Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
DOI:

09:39 min

February 07, 2021

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Chapters

  • 00:04Introduction
  • 00:49Nanoparticle (NP) Synthesis
  • 02:10Hydrogel Formulation and Rheological Property Measurement
  • 03:27In Vitro Drug Release Characterization
  • 04:35Thermal Stability of Gel-Encapsulated Insulin Characterization
  • 05:19Cell Viability Assessment
  • 06:08Cell Settling Assessment
  • 07:15Results: Representative Polymer Nanoparticle (PNP) Hydrogel Release Kinetics, Cargo Stability, and Cell Viability
  • 09:00Conclusion

Summary

Automatic Translation

Detta protokoll beskriver syntesen och formuleringen av injicerbara, supramolecular polymer-nanopartiklar (PNP) hydrogel biomaterial. Tillämpningar av dessa material för läkemedelsleverans, biofarmaceutisk stabilisering och cellinkapsling och leverans demonstreras.

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