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07:41 min
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June 08, 2022
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Summary
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Le taux de consommation d’oxygène (OCR) est un indicateur commun de la fonction mitochondriale et peut être utilisé pour étudier différents modèles de maladie. Nous avons développé une nouvelle méthode utilisant un analyseur Seahorse XF pour mesurer directement l’OCR dans les tranches striatales aiguës de souris adultes qui est plus pertinente physiologiquement que d’autres méthodes.
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Cite this Article
Zhi, L., Zhao, J., Jaffe, D., Chen, Y., Wang, N., Qin, Q., Seifert, E. L., Li, C., Zhang, H. Measurement of Oxygen Consumption Rate in Acute Striatal Slices from Adult Mice. J. Vis. Exp. (184), e63379, doi:10.3791/63379 (2022).
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