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Immunology and Infection
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Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice
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Immunology and Infection
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JoVE Journal Immunology and Infection
Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice

Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice

DOI:
10.3791/63696-v

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06:07 min

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October 06, 2022

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, , , , , ,
1Division of Hematology and Oncology, David Geffen School of Medicine,University of California, Los Angeles

Chapters

  • 00:05Introduction
  • 01:07Preparation and Administration of ART Drugs to HIV-1 Infected Mice
  • 03:59Results: A Method for Oral Administration of cART for HIV-1 Infected Humanized Mice
  • 05:38Conclusion

Summary

Automatic Translation

Automatic Translation

This protocol describes a novel method to deliver oral combinational antiretroviral drugs that successfully suppress HIV-1 RNA replication in humanized mice.

Tags

Keywords: Oral Antiretroviral TreatmentHIV-1Humanized MiceCARTFTCTDFRALELVDMSOTrimethoprim SulfamethoxazoleDrug DeliveryPreclinical StudiesHIV Cure

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