/
/
In vitro Digestione delle emulsioni in una singola goccia tramite scambio multifase di fluidi gastrointestinali simulati
A subscription to JoVE is required to view this content. Sign in or start your free trial.
1Department of Applied Physics, Faculty of Sciences, Campus de Fuentenueva,University of Granada, 2Department of Physical Chemistry, Faculty of Pharmacy, Campus de Cartuja,University of Granada, 3Department of Software Engineering, School of Computer and Telecommunication Engineering, Campus de Aynadamar,University of Granada
Chapters
- 00:05Introduction
- 02:22Calibration of the OCTOPUS
- 03:49Programming One Experimental Process in DINATEN for Each Digestive Step
- 05:51Setting up the Experiment
- 06:41Results: Gastric Digestion, Intestinal Digestion, and Complete Dynamic Gastrointestinal Digestion Profiles and Final Values of Gastrointestinal Digestion
- 09:22Conclusion
Una bilancia del film superficiale a goccia pendente implementata con uno scambio multi-sottofase, soprannominato OCTOPUS, consente di imitare le condizioni digestive mediante lo scambio sequenziale di sottofase della soluzione originale di massa con fluidi gastrointestinali simulati. La digestione simulata in vitro viene monitorata registrando in situ la tensione interfacciale dello strato interfacciale digerito.
