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A Model of Chronic Nutrient Infusion in the Rat
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JoVE Journal Medicine
A Model of Chronic Nutrient Infusion in the Rat

A Model of Chronic Nutrient Infusion in the Rat

DOI:
10.3791/50267-v

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08:18 min

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August 14, 2013

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, , , ,
1Montreal Diabetes Research Center,CRCHUM, 2Department of Medicine,University of Montreal

Chapters

  • 00:05Title
  • 01:36Cannulation of the Right Jugular Vein and the Left Carotid Artery
  • 03:12Post-surgical Treatment and Connection of the Catheters
  • 04:02Infusion
  • 05:37Monitoring
  • 06:53Representative Nutrient Infusion Results
  • 07:45Conclusion

Summary

Automatic Translation

Automatic Translation

A protocol for chronic infusions of glucose and Intralipid in rats is described. This model can be used to study the impact of nutrient excess on organ function and physiological parameters.

Tags

Chronic Nutrient InfusionRat ModelGlucose InfusionFatty Acid InfusionMetabolic SyndromeType 2 DiabetesPancreatic Beta-cellInsulin SecretionJugular Vein CatheterizationCarotid Artery CatheterizationIntralipidSoybean Oil EmulsionNutrient-induced Dysfunction

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