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Immunology and Infection
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Systemic Injection of Neural Stem/Progenitor Cells in Mice with Chronic EAE
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Immunology and Infection
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JoVE Journal Immunology and Infection
Systemic Injection of Neural Stem/Progenitor Cells in Mice with Chronic EAE

Systemic Injection of Neural Stem/Progenitor Cells in Mice with Chronic EAE

DOI:
10.3791/51154-v

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09:24 min

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April 15, 2014

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, , , ,
1Department of Clinical Neurosciences, John Van Geest Centre for Brain Repair,University of Cambridge, UK, 2NIHR Biomedical Research Center,University of Cambridge, UK

Chapters

  • 00:05Title
  • 02:00Neural Stem/Progenitor Cells (NPCs) Isolation and Infection
  • 04:34Injection of Neural/Progenitor Cells into the Tail Vein
  • 06:57Results: NPC Isolation and GFP Expression
  • 08:29Conclusion

Summary

Automatic Translation

Automatic Translation

The transplantation of neural stem/progenitor cells (NPCs) holds great promises in regenerative neurology. The systemic delivery of NPCs has turned into effective, low invasive, and therapeutically very efficacious protocol to deliver stem cells in the brain and spinal cord of rodents and nonhuman primates affected by experimental chronic inflammatory damage of the central nervous system.

Tags

Neural Stem/progenitor CellsNPC TransplantationSystemic DeliveryIntravenous InjectionIntracerebroventricular InjectionExperimental Autoimmune EncephalomyelitisEAEChronic CNS Inflammatory DemyelinationBrain RepairRegenerative Neurology

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