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Surgical Technique for the Implantation of Tissue Engineered Vascular Grafts and Subsequent In Vivo Monitoring
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Bioengineering
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JoVE Journal Bioengineering
Surgical Technique for the Implantation of Tissue Engineered Vascular Grafts and Subsequent In Vivo Monitoring

Surgical Technique for the Implantation of Tissue Engineered Vascular Grafts and Subsequent In Vivo Monitoring

DOI:
10.3791/52354-v

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11:17 min

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April 03, 2015

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, , , ,
1Department of Physiology & Bio-Physics,State University of New York Buffalo School of Medicine, 2Department of Pediatrics,State University of New York Buffalo School of Medicine, 3Department of Chemical and Biological Engineering,State University of New York Buffalo School of Engineering

Chapters

  • 00:05Title
  • 02:42Surgical Operation
  • 07:51In Vivo Monitoring
  • 09:22Results: Live In Vivo Data Acquisition of Implanted TEV
  • 09:53Conclusion

Summary

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A step-by-step protocol for the inter-positional placement of Tissue Engineered Vessels (TEVs) into the carotid artery of a sheep using end-to-end anastomosis and real-time digital assessment in vivo until animal sacrifice.

Tags

TEV ImplantationLarge Animal ModelSurgical TechniqueIn Vivo MonitoringFlow ProbesCathetersUltrasonic CrystalsArterial Blood FlowInvasive Blood PressureArtery DiameterPulse Wave VelocityAugmentation IndexPulse PressuresComplianceMatrix RemodelingNative/sham Controls

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